Author: Xin Yin [email protected] Feb 15, 2014
This directory hosts a series of tools to process the reads generated by Duplex Tag Sequencing technique developed by Schmitt et al. (2013), titled
Detection of ultra-rare mutations by next-generation sequencing
See the supplementary document of above paper for more details about the data processing pipeline.
The first stage in the data analysis: filtering by fixed sequence and tag complexity.
Perform read clustering by tags, and then pair collapsed SSCSs into pairs.