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Hi there, I am Shao, Xin and I am mainly engaged in the research of single-cell and spatial omics, cell-cell communication, and liver disease omics with machine learning and deep learning methods.
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Study and work experience - 2022-present, Hangzhou First People's Hospital Affiliated to Zhejiang University School of Medicine, Research Associate.
- 2021-present, Hangzhou First People's Hospital Affiliated to Zhejiang University School of Medicine, Postdoc. (Supervisor: Prof. Xu, Xiao/Prof. Fan, Xiaohui)
- 2015-2021, Zhejiang University, Ph.D. degree (Supervisor: Prof. Fan, Xiaohui)
- 2011-2015, Zhejiang University, Bachelor degree
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Main research articles - Shao X†, Li C†, Yang H†, Lu X, Liao J, Qian J, Wang K, Cheng J, Yang P, Chen H*, Xu X*, Fan X*. Knowledge-graph-based cell-cell communication inference for spatially resolved transcriptomic data with SpaTalk. Nat. Commun. 2022. 13(1):4429.
- Shao X†, Yang H†, Zhuang X, Liao J, Yang P, Cheng J, Lu X, Chen H*, Fan X*. scDeepSort: a pre-trained cell-type annotation method for single-cell transcriptomics using deep learning with a weighted graph neural network. Nucleic Acids Res. 2021. 49(21):e122.
- Shao X†, Liao J†, Li C†, Lu X, Cheng J, Fan X*. CellTalkDB: a manually curated database of ligand-receptor interactions in humans and mice. Brief Bioinform. 2021. 22(4):bbaa269.
- Shao X†, Lu X†, Liao J, Chen H, Fan X*. New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data. Protein Cell. 2020;11(12):866-880.
- Shao X, Liao J, Lu X, Xue R, Ai N, Fan X*. scCATCH: Automatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data. iScience. 2020;23(3):100882.
- Shao X†, Wang Y†, Lu X†, Hu Y, Liao J, Li J, Chen X, Yu Y, Ai N, Ying M, Fan X*. A Clinical Genomics-Guided Prioritizing Strategy Enables Selecting Proper Cancer Cell Lines for Biomedical Research. iScience. 2020. 23(11):101748.
- Shao X, Lv N, Liao J, Long J, Xue R, Ai N, Xu D*, Fan X*. Copy number variation is highly correlated with differential gene expression: a pan-cancer study. BMC Med. Genet. 2019. 20(1):175.
- Shao X, Ai N*, Xu D*, Fan X. Exploring the interaction between Salvia miltiorrhiza and human serum albumin: Insights from herb-drug interaction reports, computational analysis and experimental studies. Spectrochim Acta A Mol Biomol Spectrosc. 2016. 161:1-7.
- If you are interested in more details, check out my website!