Comments (1)
MarcElosua
commented on July 18, 2024
Hi @sdwien,
As long as there are enough features overlapping between the SC and ST data the deconvolution should be fine. However, from the information I can gather from your issue two possible scenarios could be that the tissue was lowly sequenced or it has low cellular density. Both of these cases will require different interpretations of the deconvolution results relying on your biological expertise!
Hope this helps, Marc
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