pyslim is a python module that provides a few extra tools for dealing with tree sequences produced by SLiM and for preparing other tree seuqences for use with SLiM. Most tree sequence functionality is provided by tskit. Please see our documentation for more information. (That link is to documentation for the last release release; instead, the latest documentation may have additional examples, but may also describe features you need to install from github to get.)

To install pyslim, do

pip install pyslim

or read the documentation for how to install from source.