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mnshgl0110 avatar mnshgl0110 commented on August 21, 2024

Ideally, in the two fasta files, sequences corresponding to the same chromosomes should have exactly same identifiers. For example:
##File1.fa

Chr1
ATGCGGAT
Chr2
GTCAAGTC

##File2.fa

Chr1
GACTATGC
Chr2
GGTCAGGT

When there is a discrepancy in the identifiers, SyRI tries to match chromosomes in the two fasta files using their alignment information. However, sometimes it is not possible to automatically match chromosomes (like in the above case). This issue can be resolved by manually fixing the chromosome identifiers, so that corresponding chromosomes in the two fasta files have exactly the same identifiers.

from syri.

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