Comments (2)
--dmr-max-dist
specifies the maximum distance to merge DMSs that have similar methylation pattern. 250bp is arbitrary to some degree but it can be justified by the observation that the methylation status of CpGs within ~200bp are correlated.
Another way to look at it is the minimum distance between two DMRs.
from methylpy.
@yupenghe cool, thanks for the explanation!
from methylpy.
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from methylpy.