Single cell classification via cell-type hierarchies based on ensemble learning and sample size estimation.
Install Bioconductor packages S4Vectors
, hopach
and limma
packages using BiocManager
:
# install.packages("BiocManager")
BiocManager::install(c("S4Vectors", "hopach", "limma"))
Then install scClassify
using devtools
:
library(devtools)
devtools::install_github("SydneyBioX/scClassify")
You can find the vignette at this webiste: https://sydneybiox.github.io/scClassify/index.html.
Also, you can find our interactive shiny application (beta) at this webiste: http://shiny.maths.usyd.edu.au/scClassify.
Currently available pre-trained scClassify models (in scClassifyTrainModel
class)
Tissue | Organism | Training Data | Accession | Summary | Download .rds |
---|---|---|---|---|---|
Primary visual cortex | mouse | Tasic (2018) | GSE115746 | link | link |
Primary visual cortex | mouse | Tasic (2016) | GSE71585 | link | link |
Visual cortex | mouse | Hrvatin | GSE102827 | link | link |
Lung | mouse | Cohen | GSE119228 | link | link |
Kidney | mouse | Park | GSE107585 | link | link |
Liver | human | MacParland | GSE115469 | link | link |
Liver | human | Aizarani | GSE124395 | link | link |
Pancreas | human | Xin | GSE81608 | link | link |
Pancreas | human | Wang | GSE83139 | link | link |
Pancreas | human | Lawlor | GSE86469 | link | link |
Pancreas | human | Segerstolpe | E-MTAB-5061 | link | link |
Pancreas | human | Muraro | GSE85241 | link | link |
Pancreas | human | Baron | GSE84133 | link | link |
Pancreas | human | joint | - | link | link |
Melanoma | human | Li | GSE123139 | link | link |
PBMC | human | Ding (joint) | - | link | link |
Tabula Muris | mouse | Tabula Muris | GSE109774 | link | link |
If you have any enquiries, espcially about performing scClassify
to classify your cells or to build your own models, please contact [email protected] or [email protected].
scClassify: hierarchical classification of cells
Yingxin Lin, Yue Cao, Hani J Kim, Agus Salim, Terence P. Speed, Dave Lin, Pengyi Yang, Jean Yee Hwa Yang
bioRxiv 776948; doi: https://doi.org/10.1101/776948