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urd's Introduction

URD

URD is an R package designed for reconstructing transcriptional trajectories underlying specification or differentiation processes in the form of a branching tree, using single cell RNA-sequencing data. It is named after the Norse mythological figure who nurtures the world tree and decides all fates.

Installation

  • To install, follow the instructions in INSTALL.md

  • To get started, check out the Quick Start Tutorial: (View) (Download)

  • The processed zebrafish embryogenesis URD object from the manuscript can be downloaded from the Broad Single-cell Portal (requires log-in).

  • The full supplementary analysis from Farrell & Wang et al. is also available

Version History

Detailed changes and minor versions are listed in NEWS.md

Most recent bugfix: 1.0.3 (May 28, 2019)

2018/04/30:

Version 1.0 released! Our manuscript, "Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis" is online!

urd's People

Contributors

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Watchers

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Forkers

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