MatLab Simulation of a simple 2-compartment lung for exploring Scond effects

These are the MatLab files for the MBW simulation used in the Paper in JAPPL. Author: G. Kim Prisk [email protected]

Submitted Jan 15, 2023

This is a deliberately simple simulation of a MBW from a 2 compartment lung. The two compartments together inspire 1 liter

The TV to each is apportioned. The FRC of each can be set

This serves to define the specific ventilation for each.

There is a simplistic sequencing parameter that determines to what degree the higher SV compartment empties early.

In order to generate a Phase III slope there needs to be SV difference -AND- sequencing. Both are required.

Sacin is not explicitly simulated, but you can add in a fized offset of SnIII that mimics this

There is no common deadsapce, or individual deadspaces, instead we use masss balance to "pretend" there is one. CO2 is fixed at 5%