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Regulatory Role of Upstream Open Reading Frames in RNA Degradation by Nonsense-Mediated Decay

Further ideas:

  • Prepare new quantification of transcripts with StringTie or something similar
  • Prior filtering of genes of with 1 exon, genes with long 3'UTRs, etc. Generally all groups of genes which may be confounding factors

Folders:

  • diagnostic_plots_files and genes_plots_files are auxiliry folders with images for .Rmd files
  • scripts - contains scripts with all preliminary data analysis
  • vkr_scripts - scripts which were used for the preparation of thesis document
  • UCSCHub - contains track and description files for UCSC Genome Browser Trackhub

Files:

  • diagnostic_plots - boxplots and scatterplots of gene expression with different pseudocounts
  • genes_plots - scatterplots of gene expression
  • filtered_transcripts.tsv & transcripts_tsv & gene_table.tsv - tables of expression (including delta) of transcripts and genes with some metadata
  • genes_vareps.tsv - table of gene expression and delta with different pseudocount
  • msigdb_result.tsv - enrichment of upregulated genes
  • positive_genes.txt - list of upregulated genes

uorf's People

Contributors

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