Genome wide association studies are designed to look for genetic markers, typically single nucleotide polymorphisms, in microarray or sequencing data associated with phenotypes – diseases or other physical characteristics. OpenSNP (https://opensnp.org) is a community “crowdsourced” project in which ordinary people can submit genotypes obtained from commercial direct-to-consumer genetic testing providers such as 23andme, along with whatever phenotypic descriptors – both physical (eye color, height) and behavioral (disposition, preferences) – that they choose to reveal.

Can we validate published genome-wide association studies of common human phenotypes using the relatively small volunteered data publicly available in OpenSNP?

You can view the report at: http://leipzig.github.io/opensnp/

You can try out building the R Markdown file in RStudio within Binder. Click the link above then start RStudio from the menu in the upper right.

See the original Binder/RStudio template and the Rocker/Binder project for more information.