Comments (2)
Hi @astrid12345,
That's a very good question! You're right that there isn't a Slingshot parameter that directly adjusts this, but you can generally get higher complexity or more branching points by adjusting the cluster labels used by Slingshot. More clusters will lead to more opportunities for branching points, so generally more complex trajectories. For example, if your input clusters were generated by k-means or Louvain clustering, you could try increasing the k
or resolution
parameters, respectively. Separately, and this might not make much of a difference, but it might be worth switching the distance metric (dist.method
) to mnn
, so that connections between clusters are based on cells in close proximity rather than overall shape.
Best,
Kelly
from slingshot.
Thank you! Those are very helpful suggestions! I will give it a go.
from slingshot.
Related Issues (20)
- Is there any way that I could fit the NB-GAM for all the gene in my large dataset? HOT 1
- getCurves() Missing values HOT 8
- Curves and lineages HOT 3
- Error in igraph::shortest_paths(tree, from = l, to = ends, mode = "out", : At core/paths/dijkstra.c:360 : Weight vector must not contain NaN values, Invalid value HOT 3
- Average curve weights and Pseudotime HOT 1
- slingshot analysis on PCA but visualization on UMAP HOT 3
- how to analyze with 3 different treatments HOT 4
- how to calclate the POS to compare other algorithm? HOT 2
- Pulling and plotting Differential pseudotime data across different conditions/metadata slots HOT 1
- `embedCurves` should also map MST into new space HOT 1
- Slingshot followed by CellRank HOT 1
- is slingshot using only the variable genes? HOT 2
- Pick one lineage from many for conditiontest HOT 3
- How do I extract feature_info in my rds file? HOT 4
- What does a curve represent biologically? HOT 7
- Overlapping curve issue - change to code needed? HOT 3
- Removing a lineage from a `PseudotimeOrdering` object? HOT 3
- Error in graph.adjacency.dense: Adjacency matrix should be symmetric to produce an undirected graph. Invalid value HOT 5
- pseudotime in two lineage? HOT 2
- Slingshot error HOT 1
Recommend Projects
-
React
A declarative, efficient, and flexible JavaScript library for building user interfaces.
-
Vue.js
🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.
-
Typescript
TypeScript is a superset of JavaScript that compiles to clean JavaScript output.
-
TensorFlow
An Open Source Machine Learning Framework for Everyone
-
Django
The Web framework for perfectionists with deadlines.
-
Laravel
A PHP framework for web artisans
-
D3
Bring data to life with SVG, Canvas and HTML. 📊📈🎉
-
Recommend Topics
-
javascript
JavaScript (JS) is a lightweight interpreted programming language with first-class functions.
-
web
Some thing interesting about web. New door for the world.
-
server
A server is a program made to process requests and deliver data to clients.
-
Machine learning
Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.
-
Visualization
Some thing interesting about visualization, use data art
-
Game
Some thing interesting about game, make everyone happy.
Recommend Org
-
Facebook
We are working to build community through open source technology. NB: members must have two-factor auth.
-
Microsoft
Open source projects and samples from Microsoft.
-
Google
Google ❤️ Open Source for everyone.
-
Alibaba
Alibaba Open Source for everyone
-
D3
Data-Driven Documents codes.
-
Tencent
China tencent open source team.
from slingshot.