Git Product home page Git Product logo

Comments (5)

jrieke avatar jrieke commented on July 18, 2024

delay_to_first_spike

At the rheobase (Ipulse = -1.90 pA or - in relation to the -12 pA holding current - at 10.10 pA) the delay to first spike becomes ~2700 ms (not shown here; can be tuned to even longer delays with a more detailed value for the rheobase).

from drosophila-dynamics.

cengique avatar cengique commented on July 18, 2024

@jrieke @borismarin : Analyzing delays in this model a bit more can be rewarding. There's an argument in the literature that Kf (Shal) channels are singlehandedly responsible for creating delays in these neurons (cf. papers by Carsten Duch et al), but as you can see in this model, we can get delays (almost) without Kf. I think a paper can be written to show to experimentalists that Kf is not the only mechanism to generate delays and also explain why the experiments may be reaching the wrong conclusion. If you guys can really pinpoint the dynamical mechanism resulting in delays, we can make a strong argument. Let me know if you're interested to explore in this direction.

from drosophila-dynamics.

borismarin avatar borismarin commented on July 18, 2024

from drosophila-dynamics.

cengique avatar cengique commented on July 18, 2024

Sounds good @borismarin ! I'd be happy to put together the literature support for my argument. Please remind me when it's closet to when you guys get together.

from drosophila-dynamics.

jrieke avatar jrieke commented on July 18, 2024

@cengique Sounds very interesting - I will put it into the list of ideas in our Google doc. Looking forward to discuss this!

from drosophila-dynamics.

Related Issues (12)

Recommend Projects

  • React photo React

    A declarative, efficient, and flexible JavaScript library for building user interfaces.

  • Vue.js photo Vue.js

    🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.

  • Typescript photo Typescript

    TypeScript is a superset of JavaScript that compiles to clean JavaScript output.

  • TensorFlow photo TensorFlow

    An Open Source Machine Learning Framework for Everyone

  • Django photo Django

    The Web framework for perfectionists with deadlines.

  • D3 photo D3

    Bring data to life with SVG, Canvas and HTML. 📊📈🎉

Recommend Topics

  • javascript

    JavaScript (JS) is a lightweight interpreted programming language with first-class functions.

  • web

    Some thing interesting about web. New door for the world.

  • server

    A server is a program made to process requests and deliver data to clients.

  • Machine learning

    Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.

  • Game

    Some thing interesting about game, make everyone happy.

Recommend Org

  • Facebook photo Facebook

    We are working to build community through open source technology. NB: members must have two-factor auth.

  • Microsoft photo Microsoft

    Open source projects and samples from Microsoft.

  • Google photo Google

    Google ❤️ Open Source for everyone.

  • D3 photo D3

    Data-Driven Documents codes.