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I’m a Senior Bioinformatics Research Scientist in Suzanne Baker’s lab in the Department of Developmental Neurobiology at St. Jude Children’s Research Hospital. We study oncohistone mutations in the context of pediatric high grade gliomas.

Other than analysis, I build useful tools and utilities for the lab and community. Recently, I created a basic utility called STRprofiler for comparing STR profiles between large collections and identifying potential sample swaps. This is particularly useful for labs that generate many cell lines/models, as we do.

Lately, I’ve been working on an R package called CRISPRball, which is largely based around a Shiny app of the same name for exploring, visualizing, and comparing CRISPR-Cas9 screens analyzed with MAGeCK. CRISPRball is now available from Bioconductor.

I am/have been involved in a handful of Bioconductor packages, including dittoSeq, SingleR, escape, and celldex.