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2020_mousefm_finemap's Introduction

2020_mousefm_finemap

For details, see our corresponding preprint:

M. Munz, M. Khodaygani, Z. Aherrahrou, H. Busch and I. Wohlers.
In silico candidate variant and gene identification using inbred mouse strains.
bioRxiv 2020.09.04.282731, 2020

Briefly, this is the workflow used for MouseFM fine-mapping of expression data, using two data sets previously utilized for eQTL identifcation based on a large number of inbred mouse strains.

Mostafavi, S., Ortiz-Lopez, A., Bogue, M. A., Hattori, K., Pop, C., Koller, D., Mathis, D., Benoist, C., and Immunological Genome Consortium.
Variation and genetic control of gene expression in primary immunocytes across inbred mouse strains.
Journal of Immunology, 193(9):4485โ€“4496, 2014

This repository contains also the script used for fine-mapping of phenotypes albinism, interfrontal bone formation and dystrophic cardiac calcification described in our preprint.

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