Calorie restriction (CR), which has the potential effect on weight loss and serum metabolism, has been demonstrated to associate with human gut microbiota. The aim of this study is to evaluate the impacts of a low-calorie diet on BMI loss, the levels of blood amino acids, the gut microbiota and their potential relationships among three parties in non-obese subjects.

This repository was used to store all the scripts of the downstream data analysis, the following zone showed the structures of the analysis directories. All the scripts named Rmd in the directory of the numeric prefix and the data resources or results were in the datset folder.

NonobeseBP/
├── 00.Phenotype
│   ├── Enterotype_classification_network.txt
│   ├── Phenotype.Rmd
│   ├── after.gsf.txt
│   ├── before.gsf.txt
│   ├── enterotype_classification_network.xlsx
│   ├── meal_calorie.Rmd
├── 01.Before
│   ├── Before.Rmd
│   └── calculate.R
├── 02.BMI
│   ├── BMI.Rmd
├── 03.Overall
│   ├── Overall.Rmd
├── 04.Amino
│   ├── Amino.Rmd
├── 05.prediction
│   ├── prediction.Rmd
├── README.md
└── datset
    ├── common
    ├── compare
    ├── correlation
    ├── diet
    ├── distance
    ├── gene.shannon.txt
    ├── pdf
    ├── phenotype
    ├── phenotype.csv
    ├── profile
    ├── reporterscore
    └── species.shannon.txt

16 directories, 23 files

1. Zou H, Wang D, Ren H, Cai K, Chen P, Fang C, Shi Z, Zhang P, Wang J, Yang H, Zhong H. Effect of Caloric Restriction on BMI, Gut Microbiota, and Blood Amino Acid Levels in Non-Obese Adults. Nutrients. 2020; 12(3):631. https://doi.org/10.3390/nu12030631