Comments (1)
Hi Laura,
Yes, you can obtain the PSI matrix for each event in each cell. The output .h5ad
file stores an AnnData object, which contains the PSI matrix by adata.layers['Psi']
, and its 95% confidence interval, adata.layers['Psi_95CI']
, if you want to filter low confident quantifications.
Also, which mode are you using? It seems the aggregated imputation fits your case:
https://brie.readthedocs.io/en/latest/brie_quant.html#mode-2-aggregated-imputation
Yuanhua
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