The targeting2019-ncov from ghddi-ailab

targeting2019-ncov's Issues

[Discuss] Workflow for causal reasoning of host response to coronavirus infection

Viral-host knowledge graph based on literature citations

Validate Causaly assertions
Provide false positives and false negatives as feedback to Causaly
Integrate Causaly assertions with general knowledge of innate immune response and related pathways

data-driven Viral-host interaction network based on pharmacological, biochemistry, and chemical biology data

Learn molecular signatures to map this data to the viral-host knowledge graph
Fill in gaps in knowledge graph

Causal reasoning over the integrated knowledge and data graph

Predict determinants of viral pathogenesis
identify targets (or combinations of targets) for medical countermeasures

Targeting 2019-nCoV R&D Discussion

Disclaimer: this discussion is limited within scientific community

Combine with efforts of SWISS-MODEL team

I noticed with great interest that you have built homology models for SARS-CoV-2 (aka 2019-nCoV) proteins using our SWISS-MODEL service. I would like to use this "feature request" to point you to our own dedicated page for modelling attempts here.

Similarly to your efforts, we envision the page to help life science researchers to get the structural data needed for their further analysis. We plan to keep the page up-to-date by including any additional useful experimental structure that appears.

So I would be happy if we can combine our efforts to provide up-to-date structural data to aid clinical researchers in their efforts to design new therapies.

[BUG] www.chictr.org.cn unavailable

I was trying to access some clinical records but unable to retrieve valid http content.

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        <title>运行时错误</title>
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         body {font-family:"Verdana";font-weight:normal;font-size: .7em;color:black;} 
         p {font-family:"Verdana";font-weight:normal;color:black;margin-top: -5px}
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         H1 { font-family:"Verdana";font-weight:normal;font-size:18pt;color:red }
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         pre {font-family:"Lucida Console";font-size: .9em}
         .marker {font-weight: bold; color: black;text-decoration: none;}
         .version {color: gray;}
         .error {margin-bottom: 10px;}
         .expandable { text-decoration:underline; font-weight:bold; color:navy; cursor:hand; }
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            <span><H1>“/”应用程序中的服务器错误。<hr width=100% size=1 color=silver></H1>

            <h2> <i>运行时错误</i> </h2></span>

            <font face="Arial, Helvetica, Geneva, SunSans-Regular, sans-serif ">

            <b> 说明: </b>服务器上出现应用程序错误。此应用程序的当前自定义错误设置禁止远程查看应用程序错误的详细信息(出于安全原因)。但可以通过在本地服务器计算机上运行的浏览器查看。
            <br><br>

            <b>详细信息:</b> 若要使他人能够在远程计算机上查看此特定错误消息的详细信息，请在位于当前 Web 应用程序根目录下的“web.config”配置文件中创建一个 &lt;customErrors&gt; 标记。然后应将此 &lt;customErrors&gt; 标记的“mode”属性设置为“Off”。<br><br>

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                      <code><pre>

&lt;!-- Web.Config 配置文件 --&gt;

&lt;configuration&gt;
    &lt;system.web&gt;
        &lt;customErrors mode=&quot;Off&quot;/&gt;
    &lt;/system.web&gt;
&lt;/configuration&gt;</pre></code>

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            <b>注释:</b> 通过修改应用程序的 &lt;customErrors&gt; 配置标记的“defaultRedirect”属性，使之指向自定义错误页的 URL，可以用自定义错误页替换所看到的当前错误页。<br><br>

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                      <code><pre>

&lt;!-- Web.Config 配置文件 --&gt;

&lt;configuration&gt;
    &lt;system.web&gt;
        &lt;customErrors mode=&quot;RemoteOnly&quot; defaultRedirect=&quot;mycustompage.htm&quot;/&gt;
    &lt;/system.web&gt;
&lt;/configuration&gt;</pre></code>

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targeting2019-ncov's Issues

[Discuss] Workflow for causal reasoning of host response to coronavirus infection

Targeting 2019-nCoV R&D Discussion

Combine with efforts of SWISS-MODEL team

[BUG] www.chictr.org.cn unavailable

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