Comments (2)
Hi
I am using raw count data from single cell RNA-seq and bulk RNA-seq.
I am currently stuck at running the deconvolution function solveDampenedWLS().
I get the error :Error in solve.QP(D, d, A, bzero) : matrix D in quadratic function is not positive definite!
I tried to solve this using nearPD() to get the nearest positive definite matrix for the data , but I still get the same error.
Can you suggest a way I can fix this issue?
Thanks a lot!
Hello,
I ran into the same error. Did you find any solution to that? Thanks
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Hi,
I solved this issue using
solution<-solve.QP(D,d,A,bzero, factorized = TRUE)$solution
instead of
# solution<-solve.QP(D,d,A,bzero)$solution
Best
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Related Issues (14)
- buildSignatureMatrixMAST does not finish HOT 1
- Is the results affected by bulkData sample size?
- Error in buildSignaturesMatrixMAST HOT 2
- Error in solve.QP(D, d, A, bzero) HOT 4
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- Issue while trying to use buildSignatureMatrixMAST function
- bulk normalization methods HOT 1
- Error message towards the end of running the script HOT 4
- Unable to install with newer version of MAST HOT 2
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- personnalised input
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