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pca_for_gwas_data's Introduction

PCA_for_GWAS_data

Features

  • PCA for GWAS data
  • できるだけnumpy以外のライブラリを使わないで実装してみる

Installation

  • numpy
  • pandas

USAGE

  1. plink形式でGWASデータを取得
  2. pedファイルから、SNPのデータを切り出す
  3. 頻度に基づき、ATGCに0か1を割り当て、ホモ:0 or 2、ヘテロ:1とする ー> 人数 x SNP数のマトリクスを得る:SNP_data.npz
  4. PCA.pyを用いて、PCAを実行する (比較のために、scikit-learnを用いたPCAも用意しています: PCA_sklearn.py)

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Contributors

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