A better focus on the host metabolism when a host is provided about metage2metabo HOT 1 OPEN

If we take as example the human gut microbiota, I think there is (at least) 2 ways to consider the host for metabolic interactions:

• the host is a direct member of the interactions and I think the way you described it with miscoto focus corresponds to this.

• the host is an environment. By its diet and the metabolic degradation of the food the host will create a set of metabolites that will correspond to the seed of the microbial community. With this behaviour I find the host to be more something like an environment (in which we expect a set of metabolites to be present) rather than an active member of the interaction. So, we should have something such as:
  Diet -> host -> processed | unabsorbed metabolites -> Microbial community -> Host
  In this case we could compute:
  Seeds -> iscope host -> new seeds (output of iscope) -> Iscope Microbial communtiy -> Comscope -> new iscope of the host with new seeds (results from comscope)

It is just an idea that I have last night so it could be wrong but I think this duality environment/active member of interaction is quite interesting.

from metage2metabo.