atomiceltaweel / bioage_rscripts Goto Github PK

Nie et al., Distinct biological ages of organs and systems identified from a multi-omics study, Cell Reports (2022), https://doi.org/10.1016/j.celrep.2022.110459

calculateKDM.R is the script for calculating biological ages for individuals in the original data set. The KDM biological ages were calculated by kdm_calc.R module.

CalculatePE.Rmd is the script for calculating parameters (k, q, s, r) for KDM model in sex-stratified samples. The results of it were merged into ‘BiologicalAgeSummaryStatistics.xlsx’.

dataPreparation_cox.R is the script for processing the data from National Health and Nutrition Examination Survey (NHANES) of the USA. The data was downloaded from cdc.gov. The analyses include calculating biological ages and cox regressions.