Comments (3)
make sure you are using the latest release version of clusterProfiler by using:
# install.packages('rvcheck')
require(rvcheck)
check_bioc("clusterProfiler")
Then follow the guideline to make a reproducible example.
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Is it possible that the score distribution has an influence? When I used as scores the logFC, which are normally distributed the function works, but when I use the expression values (of single cells) that are not normally distributed (skewed on the left, with high number of negative values) I have that error. So I just added +3 in order to remove negative values and the function worked.
Thank you very very much for you answer
Madeleine
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yes, normalized data is important for GSEA.
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Related Issues (20)
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