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svalkiers avatar svalkiers commented on September 24, 2024 1

I have identified the issue (the product of duplicated sequences resulted in higher number of sequences than the size of the data sample).

In any case, thank you so much for the quick response. I really enjoyed using CompAIRR so far! Great tool for our community :)

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torognes avatar torognes commented on September 24, 2024

By default (or with -d 0), the matching is exact. if you specify -d 1 or -d 2 or -i, also approximate matches will be included.

When you see numbers larger than 200 000 in the result for repertoire X vs X, that should be because there are two or more identical sequences (with identical V- and J-genes) within repertoire X. If you had not used the -f option, it could also have been because the count of one or more of the sequences is larger than 1.

If you have 200 000 distinct sequences and the counts are all 1, then the resulting value should have been exactly 200 000.

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torognes avatar torognes commented on September 24, 2024

Thanks for using CompAIRR! I hope you find it useful. Don't hesitate to ask more questions or suggest new features!

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