Comments (1)
Hi @ahy1221
We are indeed planning to update the prior model by incorporating some new and updated databases, but this will not be for the next few weeks.
In this vignette https://github.com/saeyslab/nichenetr/blob/master/vignettes/model_construction.md,
you can see how to incorporate your new data source with new ligand-receptor pairs and build a customized NicheNet prior model. I would suggest you just add your new data source to the existing ones, and give your new data source as weight 1, and use the optimized weights for the other data sources.
Please let me know if you would have any more questions about this.
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Related Issues (20)
- I can't install nichenet HOT 1
- Condition_colname is not used for subsetting in nichenet_seuratobj_aggregate HOT 2
- `make_line_plot` bugs
- `assign_ligands_to_celltype` bug when there are no general ligands
- Error in `generate_info_tables`
- Warning message in `predict_ligand_activities`
- `generate_prioritization_tables` warnings and documentation
- Error when passing the recorrect_umi argument in get_lfc_celltype HOT 1
- Error in WhichCells.Seurat(object = object, idents = ident.2) : Cannot find the following identities in the object: Adjacent HOT 1
- Error in `Idents<-`: ! 'value' must be a factor or vector HOT 3
- Different results running. the same. code in different version. of HOT 6
- Protein complex HOT 1
- Function generate_info_tables return an error HOT 3
- Low AUPR values in analyses HOT 4
- RankActiveLigands Error
- Can NicheNet be used for analyzing three groups? HOT 1
- Parallelization error when optimizing parameters for NicheNet HOT 4
- How is the Ligand-Target-Matrix generated? HOT 2
- Receiver cells in differential analysis HOT 1
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