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Laurens van de Wiel's Projects

datasciencenotebook icon datasciencenotebook

A general purpose clean example on how to construct R and Python notebooks using Docker

keco icon keco

An implementation to a kernel based co-agreement algorithm

positive-selection icon positive-selection

Scripts and procedures for detecting positively selected genes and codons in primates

pubgenie icon pubgenie

PUBGENIE (PUBlishedGENEvaRIantIdentifier) is a lightweight web server designed to explore and identify variants published in rare disease publications

snv-scape icon snv-scape

Generates a VCF of the Single Nucleotide Variant Mutational Space of a genomic region or gene based on the Reference Genome

spatialclustering icon spatialclustering

The spatial clustering algorithm used for the publication "Spatial Clustering of De Novo Missense Mutations Identifies Candidate Neurodevelopmental Disorder-Associated Genes" (https://doi.org/10.1016/j.ajhg.2017.08.004)

toga icon toga

TOGA (Tool to infer Orthologs from Genome Alignments): implements a novel paradigm to infer orthologous genes. TOGA integrates gene annotation, inferring orthologs and classifying genes as intact or lost.

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