jhhughes256 Goto Github PK
Name: Jim Hughes
Type: User
Company: Pfizer
Location: United States
Name: Jim Hughes
Type: User
Company: Pfizer
Location: United States
Estimation of rate constant parameters for the acid/base attack of aspirin. Post-graduate work for Dr. Desmond Williams at University of South Australia.
Web application, raw code and digitised data for published manuscript: Hughes, J.H., Sweeney, K., Ahadieh, S. and Ouellet, D. (2020), Predictions of Systemic, Intracellular, and Lung Concentrations of Azithromycin with Different Dosing Regimens used in COVID‐19 Clinical Trials. CPT Pharmacometrics Syst. Pharmacol. Application can be found at:
Calcium Caffeine Model Simulations. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
Dosing application for manuscript: Harris, B.D.W., Phan, V., Perera, V. et al. Inability of Current Dosing to Achieve Carboplatin Therapeutic Targets in People with Advanced Non-Small Cell Lung Cancer: Impact of Systemic Inflammation on Carboplatin Exposure and Clinical Outcomes. Clin Pharmacokinet (2020). https://doi.org/10.1007/s40262-020-00870-6 - Web App can be found at:
Web applications for use with compositional data. Post-graduate work for Dr. Dot Dimuid and Prof. Timothy Olds at University of South Australia.
Empirical MAP Bayes examples and applications. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Rozewski DM, Phelps MA, Foster DJR. Development of a physiologically-based pharmacokinetic model for intravenous lenalidomide in mice.
Raw R code used in manuscript: Hughes JH, Phelps MA, Upton RN, et al. Population pharmacokinetics of lenalidomide in patients with B-cell malignancies. Br J Clin Pharmacol. 2019;85(5):924-934.
Raw R code used in manuscript: Hughes JH, Upton RN, Foster DJR. Comparison of non-compartmental and mixed effect modelling methods for establishing bioequivalence for the case of two compartment kinetics and censored concentrations. J Pharmacokinet Pharmacodyn. 2017:1-12.
Raw R code used in draft manuscript: Hughes JH, Roussin-Bouchard U, Wang Y, Boddy AV, Reuter SE. Reduction of Nivolumab Dosing using Adaptive-Dosage Strategies
Raw R code for manuscript: Hughes JH, Upton RN, Reuter SE, Phelps MA, Foster DJR. Optimising time samples for determining AUC of pharmacokinetic data using non-compartmental analysis.
R code for manuscript: Hughes JH, Upton RN, Reuter SE, Phelps MA, Foster DJR. Optimising time samples for determining AUC of pharmacokinetic data using non-compartmental analysis. - Web App can be found at:
Course materials for "Introduction to Shiny" internal course given in November 2020
R code of Shiny workshop presented at PAGANZ 2017 in Adelaide.
Public apps and examples
Raw R code for simulations using South Australia Health Guidelines for vancomycin dosing. Post-graduate work for Dr. Stephanie Reuter-Lange at University of South Australia.
A declarative, efficient, and flexible JavaScript library for building user interfaces.
🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.
TypeScript is a superset of JavaScript that compiles to clean JavaScript output.
An Open Source Machine Learning Framework for Everyone
The Web framework for perfectionists with deadlines.
A PHP framework for web artisans
Bring data to life with SVG, Canvas and HTML. 📊📈🎉
JavaScript (JS) is a lightweight interpreted programming language with first-class functions.
Some thing interesting about web. New door for the world.
A server is a program made to process requests and deliver data to clients.
Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.
Some thing interesting about visualization, use data art
Some thing interesting about game, make everyone happy.
We are working to build community through open source technology. NB: members must have two-factor auth.
Open source projects and samples from Microsoft.
Google ❤️ Open Source for everyone.
Alibaba Open Source for everyone
Data-Driven Documents codes.
China tencent open source team.