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Hello ✨ I am Daniel!

My website is here and this is my GitHub Portfolio.

  • 🔭 My present graduate studies is in Multiomics, Genome Bioinformatics, and Computational Biology and my previous research has been in multiple areas and fields of Medicine: Tropical Medicine, Medical Microbiology, Pharmacology, Cell and Molecular Biology, Microbiology and Immunology, Structural Biology, Infectious Disease, Bioengineering, and Cancer Biology.

  • Presently, I am doing my thesis research in exercise medicine, multiomics, creating spatial maps at single-cell resolution.

Research:

  • Precision Bioinformatics
  • Exerkines and Exercise
  • Mechanisms that underlie the benefits of exercise (exercise science research)
  • Exercise Biochemistry, Molecular Biology, and Physiology
  • Precision Medicine to Network Medicine
  • Computational biology
  • Spatial Multi-Omics and Multiplex Imaging
  • Single-cell biology (scATACseq, scRNAseq, snRNAseq, etc)
  • Developing analytical tools to harness both high-dimensional single-cell phenotype data and spatial info
  • Spatial analysis of tissue architecture & cellular niches
  • Annotating spatially resolved single-cell data by spatial cell learning
  • Multi-omics multi-tissue molecular mapping (Tissue- and Organism-Wide Multi-omics)
  • Molecular Bioengineering, Nanotechnology, Nanomedicine, and Cell and Gene Thereapy
  • Computational Medicine Physiology

Technique Interests:

  • Genomics and Proteomics, Metabolomics (multiomics), Structural Variations and Predictions
  • Systems Biology and Applications
  • Biological Modeling and Evaluation, Drug Development
  • Data visualization, Data analysis, Data mining
  • Biological and Disease Modeling (AI/ML/DL)
  • Molecular neuroimmune-pathology, psychoneuroimmunology (PNI), neuroimmunopharmacology (NIP)
  • Neurotherapeutics discovery
  • Neuroimmune connectome, neuropathology and neuroimaging modalities (PET, fMRI BOLD, dMRI, DWI, FLAIR, DTI, PWI, MEG, HARDI, Q-balls)
  • multimodal neuronavigation for neurosurgery, ie BrainLab
  • Morphology and imaging (histology, live-cell, all kinds of microscopy)

Twitter: @dan_j_gomez

Skills

  • Data Science and Cloud Computing of Precision Medicine

  • Bioinformatics and Computational Biology Tools

  • Data Analysis and Data Visualization

  • Computational Genomics and Genetics

  • Statistical analysis and computing

  • Basic Lab & Safety (GMP, BBP, IRB)

  • Cell viability assays (whole blood)

  • Funcational assay development and experimental design

  • Sequence analysis

  • DNA isolation

  • PCR (qPCR), Sequencing (Sanger, capillary, NGS), & Fragment Analysis

  • Phylogenetics

  • Plasmid Minipreps

  • RNA isolation

  • Protein Purifcation

  • Protein Harvesting

  • Gel Electrophoresis (DNA and Protein (SDS-PAGE))

  • Protein concentration assays (e.g. Bradford assay)

  • Tissue (in situ) experiments (immunohistochemistry, in situ hybridization)

  • Surgical methods in whole animal (in toto) to organ isolation (ex vivo), brain tumor resection and dissections

  • Machine Learning & Generative AI

  • Deep Learning, Reinforcement Learning

  • Processing large data sets

  • Neural networks

  • Data Analysis

  • Big Data and Omics

  • Single Cell Research and Spatial Multiomics

Future Directions 👨‍💻

- Research Assistant/Associate/Scientist - Biomedical Data Science Engineer - Molecular Biologist / Genome Engineer - Clinical Bioinformatician - Computational Biologist

Hobbies

  • Exercising (strength and functional training) (cardiovascular actviity, circuit training) working out
  • Hiking, Cycling, and Climbing
  • Reading, Listening to Audiobooks and Podcasts
  • Music (DJ) and Movies
  • Astrophysics and Astrobiology exploration

Daniel J. Gomez's Projects

assemblytics icon assemblytics

Assemblytics is a bioinformatics tool to detect and analyze structural variants from a genome assembly by comparing it to a reference genome.

biofx_python icon biofx_python

Code for Mastering Python for Bioinformatics (O'Reilly, 2021, ISBN 9781098100889)

bioinformatics icon bioinformatics

Pyt notes on generating DNA test data, determining the GC-Content, Reverse complement, Hamming distance, Finding motifs, Rabbits, Calculating minimum skew, Hidden Markov Models

chm13 icon chm13

The complete sequence of a human genome

galaxy icon galaxy

Data intensive science for everyone.

gtex-v8 icon gtex-v8

Notebooks and scripts for reproducing analyses and figures from the V8 GTEx Consortium paper

liana-py icon liana-py

LIANA+: an all-in-one framework for cell-cell communication

ns5b-rdrp icon ns5b-rdrp

This is my Virophysics (Structural Predictions) on GBV-C/HPgV-1 's RNA-dependent RNA polymerase (RdRp) NS5B

nucamino icon nucamino

A nucleotide to amino acid alignment program optimized for virus gene sequences.

ostn-tfr1 icon ostn-tfr1

Structural predictions of musclin (osteocrin) and transferrin receptor 1 (OSTN-TFR1) (AlphaFold2, ESMfold)

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