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Kleinman Lab's Projects

braindex icon braindex

A web portal for exploring scRNAseq data in the developing brain, including our in-house atlas of the E10-P6 forebrain and brainstem

chromswitch icon chromswitch

An R/Bioconductor package for detecting chromatin state switches

chromswitch-analysis icon chromswitch-analysis

Code and data to accompany the chromswitch paper, "chromswitch: A flexible method for detecting chromatin state switches" (Jessa and Kleinman, Bioinformatics, 2018)

cytobox icon cytobox

A toolbox for analysis and highly-customizable visualization of single cell data

g34-gliomas icon g34-gliomas

Cell-of-origin analysis for "Histone H3.3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis" (Chen*, Deshmukh*, Jessa*, Hadjadj*, et al, Cell, 2020)

hgg-oncohistones icon hgg-oncohistones

Analysis for "K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas" (Jessa et al, Nature Genetics, 2022)

sccoannotate icon sccoannotate

Pipeline for consensus prediction of cell types in single-cell RNA sequencing data.

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