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eweitz avatar eweitz commented on August 16, 2024

Hi Tong, take a look at paralog neighborhoods, which address a similar use case. The HOXA1 view in gene leads ideogram also shows paralog neighborhoods (sometimes called paralogy regions). Hovering over the pink overlay annotations there shows a tooltip with brief data on genomically clustered features that are too close together to see with typical triangles beside the chromosome.

I hesitate to add zooming in Ideogram.js, as that strongly overlaps with mature products like igv.js and JBrowse that focus on small regions. However, integrations between Ideogram and those other genome browsers might suit your use case. Additionally, if something like paralog neighborhoods seem valuable, maybe that feature could be refined and generalized for use cases like yours.

Let me know your thoughts! Also, could you tell me where you're using Ideogram? Knowing more about groups and applications using Ideogram helps guide my development.

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Tong-Chen avatar Tong-Chen commented on August 16, 2024

Thanks for your quick response. I have checked this paralog show before but ignored the hover box. This does give detailed information on all genes in this local region.

I am also using IGV.js which could show very close genes. This also could show neighbor genes clearly. Before I just thought if there is any way to accomplish this job just be ideogram.js. I also checked the brush function which is close to some content.

I am using ideogram.js to check if several genes could form gene clusters in the IMP website.

Thanks again for this development and answers.

Tong

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