Clickonce - conditionally updating update location about deployment-tools HOT 6 OPEN

This is a bit of a fishing expedition here as I am trying to understand if this is possible, and if so how I might start investigating. We have an app that is updated from a central location. We also have a series of Clients, each with their own azure app services. We are wanting to move our installer so it is updated from each Client's app service rather than just having one installer for all Clients. We would then deploy our app automatically to each Client's app service. Obviously this enables us to deploy early versions to Client's with specific bugfixes etc. without affecting the general environment.

I know it is possible to change the deployment location after deployment by just updating the property between updates. Is it possible to conditionally do this - e.g. update the manifest client side based on a database setting, thus rewriting the UpdateUrl with an updated location? I think technically this should be OK as it doesn't change the ApplicationId