dashing2 for metagenome about dashing2 HOT 1 OPEN

Hi Jianshu -

Interesting. Yes, you can collapse them together. A lot depends on if the two ends overlap with each other. You can safely concatenate the sequences with an N between - Dashing and Dashing2 will mask any k-mers with unknown k-mers, so you'll end up with one k-mer set for the paired-end reads.

Normally you could just concatenate the files directly since they end up in the same bucket. But you are right, any preprocessing can make things smaller.

And to check in about DartMinHash - I've worked on incorporating its weighted minhashing scheme but I haven't had time to test accuracy results and merge it in. If it helps us with weighted sketching, it would really help cut out the costs of --bagminhash weighted sketching.

Sorry for the delay!

Thanks,

Daniel

from dashing2.