Comments (2)
Multi-fasta files weren't originally supported because Kraken used to use a file that mapped files to taxa. (This made sense when working only with completed microbial genomes, but has since been shown to be problematic.) One of the component programs, set_lcas, would then open each file one at a time, and use the map information to assign correct taxonomic information to the file's k-mers. The set_lcas program actually supported multi-fasta files for quite a while, but the scripts and changes to other programs to support those files weren't present until now.
As of the most recent commit, adding multi-fasta files to a DB should no longer require many, many files in the filesystem, and also will not utilize the clumsy .ffn hack that just confused matters and ate up disk space unreasonably.
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Thanks @DerrickWood . That helps tremendously.
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